All of us at some time or other have had times in our lives when we have not dealt with some difficulty that has arisen. By dealing with it I mean that we have not addressed it emotionally. It has been left unresolved and every now and then it comes to the forefront and evokes a negative emotional response, a inner hurt. For some people there are many of these unresolved issues that sap emotional energy and have the effect of stopping them moving on, effectively keeping them a prisoner with themselves as the gaoler.
The starting point to change is this: YOU CAN NOT CHANGE THE PAST, what's gone is gone, you now have to live with the effects. What you can change is the perception you ha
Over the centuries, new medical developments and techniques have changed the face of healthcare. The medical field has always brought together the best and brightest of society to help those in need. From treating cancer and delivering babies to dealing with heart attacks, doctors have
NEW YORK--(BUSINESS WIRE)--Dr. Tim van Biesen, a leading authority in pharmaceutical industry
strategy, has been named head of Bain & Company's Healthcare Practice in
North America. His appointment was announced by Dr. Norbert
Hueltenschmidt, who leads Bain's Healthcare Practice globally. Dr. van
Biesen is based in the firm's New York office.
Dr. van Biesen advises Bain's clients in the areas of growth, R&D and
brand strategy. He has also led significant client engagements in
licensing and acquisitions, post-merger integration, manufacturing and
supply chain strategy. His deep expertise spans across the healthcare
A study by investigators from Costa Rica and the National Cancer Institute provides reassurance about the safety of human papillomavirus (HPV) vaccination for women who may become pregnant soon after receiving the vaccine. The findings, published in BMJ, show no increased risk of miscarriage for pregnancies conceived <90 days after vaccination, adding to results of an earlier study that found a similar trend for pregnancies conceived 90 days after vaccination.
Conducted in Costa Rica, the observational single-center study represented long-term follow up of a randomized double-blind trial combined with an independent, unvaccinated population-based cohort. The participants were 7466 women in the trial and 2836 women in the unvaccinated cohort who enrolled at the end of the randomized trial and in parallel with the observational trial component.
Recommended: Is 1 dose of HPV vaccine pr in healthcare offers great jobs as effective as 3?
Women in the trial were randomized to 3 doses of either the experimental bivalent HPV L1 virus-like particle AS04 vaccine (n=3727) or the control hepatitis A vaccine (n=3739). Crossover bivalent HPV vaccination occurred in the hepatitis A vaccine arm at the end of the trial. Women in the unvaccinated cohort (n=2836) received no vaccination and were enrolled to allow continued evaluation of efficacy and safety of the vaccine despite loss of the original controls because of the crossover vaccination.
Of the 3394 pregnancies that occurred at any time after HPV vaccination, 318 were conceived <90 days after vaccination. Unexposed pregnancies comprised 2507 pregnancies conceived after hepatitis A vaccination and 720 conceived in the women who had not been vaccinated.
Miscarriages occurred in 451 (13.3%) of the exposed pregnancies, 50 (13.1%) of the pregnancies conceived <90 days after HPV vaccination, and 414 (12.8%) of the unexposed pregnancies. Of the latter pregnancies, 316 (12.6%) were in the hepatitis A vaccine group and 98 (13.6%) in the unvaccinated cohort. The relative risk (RR) for miscarriage of pregnancies conceived <90 days after vaccination versus all unexposed pregnancies was 1.02 (95% confidence interval [CI] 0.78 to 1.34, one sided P=0.436) in unadjusted analyses. Results were similar after adjustment for age at vaccination, age at conception, and calendar year, and in stratified analyses.
For pregnancies conceived at any time after HPV vaccination, exposure to the vaccine was not associated with an increased risk of miscarriage overall or in subgroups, except for miscarriages at weeks 13 to 20 of gestation (RR 1.35, 95% CI 1.02 to 1.77, one sided P=0.017). The outcome in this subgroup, the authors said, is compatible with chance and may be an artifact of a thorough set of sensitivity analyses. However, because they could not totally rule out a genuine association, the investigators recommend further exploration in ongoing and future studies. Curiously, the rate of miscarriages at 13 to 20 weeks in the women exposed to hepatitis A vaccine was lower than that in both the HPV-vaccinated group and the women who had no vaccination.
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- Dealing With Unresolved Issues
- How Technology Is Changing the Medical and Health Care Field
- Bain & Company Selects Tim van Biesen, Pharmaceutical Industry Expert, to Lead the Consulting Firm’s Healthcare Practice in North America
- New data show no miscarriage link for HPV vaccination
- Ways To The Skin Healthy